Depression is a common mental illness, affecting more than 300 million people worldwide.
Decades of investigation have yielded symptomatic therapies for this disabling condition but …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Objective: Although brain changes in schizophrenia have been proposed to mirror those
found with advancing age, the trajectory of gray matter and white matter changes during the …

Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

In recent years, escitalopram (ESC) has been suggested to have different mechanisms of
action beyond its well known selective serotonin reuptake inhibition. The aim of this study is …

Background: Lipid profile disturbances are frequently observed in major depressive disorder
(MDD) and constitute to high mortality rates. However, less is known about whether this risk …

Depressive disorders are complex, multifactorial disorders that have been traditionally
attributed exclusively to neuronal abnormalities. However, recent studies have increased …

Oligodendrogenesis and oligodendrocyte precursor maturation are essential processes
during the course of central nervous system development, and lead to the myelination of …

Depressive disorder is the most prevalent affective disorder today. Depressive disorder has
been linked to changes in the white matter. White matter changes in depressive disorder …

Background Numerous cortical and subcortical structures have been studied extensively
concerning alterations of their integrity as well as their neurotransmitters in depression …