Mobile elements and repetitive genomic regions are sources of lineage-specific genomic
innovation and uniquely fingerprint individual genomes. Comprehensive analyses of such …

LINE-1 (L1) is a class of autonomous mobile genetic elements that form somatic mosaicisms
in various tissues of the organism. The activity of L1 retrotransposons is strictly controlled by …

INTRODUCTION The rhesus macaque (Macaca mulatta) is one of the most widely used
nonhuman primate (NHP) models for studying human biology and disease. As a …

Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells
throughout the body. Although well-annotated coding and non-coding transcripts in blood …

Associations of chromatin with the nuclear lamina, at the nuclear periphery, help shape the
genome in 3 dimensions. The genomic landscape of lamina-associated domains (LADs) is …

The human endogenous retrovirus type-H (HERVH) family is expressed in the
preimplantation embryo. A subset of these elements are specifically transcribed in …

Genome-wide association studies (GWAS) have been highly informative in discovering
disease-associated loci but are not designed to capture all structural variations in the human …

Study of repetitive DNA elements in model organisms highlights the role of repetitive
elements (REs) in many processes that drive genome evolution and phenotypic change …

Piwi interacting RNAs (piRNAs) are small non-coding single-stranded RNA species 20–31
nucleotides in size generated from distinct loci. In germline tissues, piRNAs are amplified via …

Genome annotation is an important but challenging task. Accurate identification of short
interspersed nuclear elements (SINEs) is particularly difficult due to their lack of highly …