Acute ischemic stroke (AIS) is a focal neurological disorder that accounts for 85% of all
stroke types, due to occlusion of cerebral arteries by thrombosis and emboli. AIS is also …

Drug-induced organic damage encompasses various intricate mechanisms, wherein
HMGB1, a non-histone chromosome-binding protein, assumes a significant role as a pivotal …

Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

Amphotericin B (AmB)–induced acute kidney injury (AKI) is a common health problem
having an undesirable impact on its urgent therapeutic utility for fatal systemic fungal …

The aim of this study is to explore the potential of repurposing the antiarthritic drug diacerein
(DCN) against diclofenac (DCF)-induced acute nephrotoxicity in rats. Rats were divided into …

Despite being a potent anticancer drug, cisplatin has limited applicability due to its adverse
effects, such as testicular damage. Consequently, reducing its toxicity becomes necessary …

Although diclofenac (DCF) is a nonsteroidal anti‐inflammatory drug that is considered safe,
its chronic use and overdose may show some toxic effects. The protective effect of tyrosol …

The development of new drugs for the inhibition of hepatocellular carcinoma (HCC)
development and progression is a critical and urgent need. The median survival rate for …

Diclofenac (DF)-induced acute kidney injury (AKI) is characterized by glomerular dysfunction
and acute tubular necrosis. Due to limited treatment approaches, effective and safe drug …

The vascular endothelium is not only the semipermeable membrane that separates tissue
from blood but also an organ that regulates inflammation, vascular tone, blood clotting …