ICARUS v3, a massively scalable web server for single-cell RNA-seq analysis of millions of cells
Motivation In recent years, improvements in throughput of single cell RNA-seq have resulted
in a significant increase in the number of cells profiled. The generation of single cell RNA …
in a significant increase in the number of cells profiled. The generation of single cell RNA …
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model
Huntington's disease (HD) is a neurodegenerative genetic disorder caused by an expansion
in the CAG repeat tract of the huntingtin (HTT) gene resulting in behavioural, cognitive, and …
in the CAG repeat tract of the huntingtin (HTT) gene resulting in behavioural, cognitive, and …
Construction of multilayered small intestine-like tissue by reproducing interstitial flow
S Deguchi, K Kosugi, N Takeishi, Y Watanabe… - Cell Stem Cell, 2024 - cell.com
Recent advances have made modeling human small intestines in vitro possible, but it
remains a challenge to recapitulate fully their structural and functional characteristics. We …
remains a challenge to recapitulate fully their structural and functional characteristics. We …
scRNA-Explorer: An end-user online tool for single cell RNA-seq data analysis featuring gene correlation and data filtering
In the majority of downstream analysis pipelines for single-cell RNA sequencing (scRNA-
seq), techniques like dimensionality reduction and feature selection are employed to …
seq), techniques like dimensionality reduction and feature selection are employed to …
Evidence for glutamate excitotoxicity that occurs before the onset of striatal cell loss and motor symptoms in an ovine Huntington's Disease model
Background Huntington's disease (HD) is a neurodegenerative genetic disorder caused by
an expansion in the CAG repeat tract of the huntingtin (HTT) gene resulting in a triad of …
an expansion in the CAG repeat tract of the huntingtin (HTT) gene resulting in a triad of …
[PDF][PDF] Generation of a large animal model of Fragile X Syndrome for therapeutic testing
VEK Hawkins - researchspace.auckland.ac.nz
Fragile X syndrome (FXS) is an X-linked neurodevelopmental condition. For most FXS
individuals, symptoms result from hypermethylation of an expanded CGG repeat in the …
individuals, symptoms result from hypermethylation of an expanded CGG repeat in the …