Skyline is a freely available, open‐source Windows client application for accelerating
targeted proteomics experimentation, with an emphasis on the proteomics and mass …

One‐carbon metabolism is a metabolic network that integrates nutrient status from the
environment to yield multiple biological functions. The folate and methionine cycles …

Vendor-independent software tools for quantification of small molecules and metabolites are
lacking, especially for targeted analysis workflows. Skyline is a freely available, open-source …

Ovarian cancer is the deadliest gynecologic cancer. Despite recent advances, clinical
outcomes remain poor, necessitating novel therapeutic approaches. To investigate …

Ferroptosis is a specialized iron-dependent cell death that is associated with lethal lipid
peroxidation. Modulation of ferroptosis may have therapeutic potential since it has been …

Critical to the bacterial stringent response is the rapid relocation of resources from
proliferation toward stress survival through the respective accumulation and degradation of …

Resistance to chemotherapeutic agents remains a major challenge in the fierce battle
against cancer. Cancer stem cells (CSCs) are a small population of cells in tumors that …

Ferroptosis is a newly described form of regulated cell death triggered by oxidative stresses
and characterized by extensive lipid peroxidation and membrane damages. The name of …

Rapid increase in aging populations is an urgent problem because older adults are more
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …

Tumor progression upon treatment arises from preexisting resistant cancer cells and/or
adaptation of persister cancer cells committing to an expansion phase. Here, we show that …