Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …

Ion homeostasis is extremely important for the survival of both normal as well as neoplastic
cells. The altered ion homeostasis found in cancer cells prompted the investigation of …

Recently, the interplay between autophagy and apoptosis has become an important factor in
chemotherapy for cancer treatment. Inhibition of autophagy may be an effective strategy to …

Ovarian cancer is one of the most important malignancies, and the origin, detection, and
pathogenesis of epithelial ovarian cancer remain elusive. Although many cancer drugs have …

Cancer is a complex group of diseases initiated by abnormal cell division with the potential
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …

Background Anthracyclines are efficient and potent agents to treat broad range of cancers
but cytotoxicity induced by them limits their use in therapeutics. Use of plant-derived agents …

Purpose To develop immunoliposomes modified with monoclonal cancer-specific antibody
(mAb) 2C5 and co-loaded with a combination of two chemotherapeutics, in order to …

ATP-binding cassette (ABC) transporters are transmembrane proteins expressed commonly
in metabolic and excretory organs to control xenobiotic or endobiotic disposition and …

Tumors are phenotypically heterogeneous and include a small sub-population of cancer
cells (2–5% of the tumor mass) with stem-cell like properties. The cancer stem cell …

Triple‑negative breast carcinoma (TNBC) is one of the most aggressive subtypes of breast
cancer and is associated with an unfavorable prognosis. The management of TNBC is …