Deep Sequencing Reveals Compartmentalized HIV-1 in the Semen of Men with and without STI-associated Urethritis

OD Council, S Zhou, CD McCann, I Hoffman, G Tegha… - bioRxiv, 2020 - biorxiv.org
Concurrent sexually transmitted infections (STI) can increase the probability of HIV-1
transmission primarily by increasing the viral load present in semen. In this study, we …

[PDF][PDF] Th1/17 polarization of CD4 T cells supports HIV-1 DNA persistence during antiretroviral therapy 2

HS Vandekerckhove, ES Rosenberg, XG Yu… - 2015 - researchgate.net
The ability to persist long term in latently-infected CD4 T cells represents a characteristic
feature 35 of HIV-1 infection and the predominant barrier to efforts aiming at viral eradication …