Optical imaging represents one of the most essential tools in biological studies. Although
with great advances, bio-optical imaging still suffers from problems such as resolution …

Advances in microscopy and molecular strategies have allowed researchers to gain insight
into the intricate organization of the mammalian brain and the roles that neurons play in …

Manipulating topological arrangement is a powerful tool for tuning energy migration in
natural photosynthetic proteins and artificial polymers. Here, we report an inorganic optical …

Cytoplasmic dynein is essential for intracellular transport. Despite extensive in vitro
characterizations, how the dynein motors transport vesicles by processive steps in live cells …

In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …

Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Intracellular transport plays an essential role in maintaining the organization of polarized
cells. Motor proteins tether and move cargos along microtubules during long-range transport …

Biological systems have evolved biochemical, electrical, mechanical, and genetic networks
to perform essential functions across various length and time scales. High-aspect-ratio …

Dynamin has an important role in clathrin-mediated endocytosis by cutting the neck of
nascent vesicles from the cell membrane. Here, using gold nanorods as cargos to image …

Background In the intracellular environment, motor-driven cargo must navigate a dense
cytoskeletal network among abundant organelles. Results We investigated the effects of the …