DNA nanotechnology approaches for microRNA detection and diagnosis

AR Chandrasekaran, JA Punnoose, L Zhou… - Nucleic acids …, 2019 - academic.oup.com
MicroRNAs are involved in the crucial processes of development and diseases and have
emerged as a new class of biomarkers. The field of DNA nanotechnology has shown great …

RNA-sequencing analyses of small bacterial RNAs and their emergence as virulence factors in host-pathogen interactions

I Diallo, P Provost - International journal of molecular sciences, 2020 - mdpi.com
Proteins have long been considered to be the most prominent factors regulating so-called
invasive genes involved in host-pathogen interactions. The possible role of small non …

Evolution of flower color pattern through selection on regulatory small RNAs

D Bradley, P Xu, II Mohorianu, A Whibley, D Field… - Science, 2017 - science.org
Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that population-
wide differences in color patterns in snapdragon flowers are caused by an inverted …

The UEA sRNA Workbench (version 4.4): a comprehensive suite of tools for analyzing miRNAs and sRNAs

MB Stocks, I Mohorianu, M Beckers, C Paicu… - …, 2018 - academic.oup.com
Motivation RNA interference, a highly conserved regulatory mechanism, is mediated via
small RNAs (sRNA). Recent technical advances enabled the analysis of larger, complex …

Biosensing: The best alternative for conventional methods in detection of Alzheimer's disease biomarkers

A Mobed, M Hasanzadeh - International journal of biological …, 2020 - Elsevier
Conceivably the imperative reason for the absence of appropriate treatment for Alzheimer's
disease (AD) is the late onset of clinical symptoms followed by late treatment. Specific …

Comparison of alternative approaches for analysing multi-level RNA-seq data

I Mohorianu, A Bretman, DT Smith, EK Fowler… - PLoS …, 2017 - journals.plos.org
RNA sequencing (RNA-seq) is widely used for RNA quantification in the environmental,
biological and medical sciences. It enables the description of genome-wide patterns of …

A survey of software tools for microRNA discovery and characterization using RNA-seq

M Bortolomeazzi, E Gaffo… - Briefings in bioinformatics, 2019 - academic.oup.com
Since the small RNA-sequencing (sRNA-seq) technology became available, it allowed the
discovery of thousands new microRNAs (miRNAs) in humans and many other species …

RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database

PR Bushel, F Caiment, H Wu, R O'Lone, F Day… - Bmc Genomics, 2018 - Springer
Background MicroRNAs (miRNAs) regulate gene expression and have been targeted as
indicators of environmental/toxicologic stressors. Using the data from our deep sequencing …

miRToolsGallery: a tag-based and rankable microRNA bioinformatics resources database portal

L Chen, L Heikkinen, CL Wang, Y Yang, KE Knott… - Database, 2018 - academic.oup.com
Hundreds of bioinformatics tools have been developed for MicroRNA (miRNA)
investigations including those used for identification, target prediction, structure and …

Identification of alternatively spliced gene isoforms and novel noncoding RNAs by single-molecule long-read sequencing in Camellia

Z Hu, T Lyu, C Yan, Y Wang, N Ye, Z Fan, X Li, J Li… - RNA biology, 2020 - Taylor & Francis
Direct single-molecule sequencing of full-length transcripts allows efficient identification of
gene isoforms, which is apt to alternative splicing (AS), polyadenylation, and long non …