[HTML][HTML] Research progress of sorafenib drug delivery system in the treatment of hepatocellular carcinoma: an update

Q Fan, H Tian, J Cheng, J Zou, F Luan, J Qiao… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant tumors in the
contemporary era, representing a significant global health concern. Early HCC patients have …

Recent advances on chitosan/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: A comprehensive review

F Alsaikhan, B Farhood - International Journal of Biological …, 2024 - Elsevier
Cancer, as leading cause of death, has a high rate of mortality worldwide. Although there is
a wide variety of conventional approaches for the treatment of cancer (such as surgery and …

[HTML][HTML] Graphene Quantum Dots from Natural Carbon Sources for Drug and Gene Delivery in Cancer Treatment

HM Osorio, F Castillo-Solís, SY Barragán… - International Journal of …, 2024 - mdpi.com
Cancer therapy is constantly evolving, with a growing emphasis on targeted and efficient
treatment options. In this context, graphene quantum dots (GQDs) have emerged as …

Nano‐and Micro‐Platforms in Therapeutic Proteins Delivery for Cancer Therapy: Materials and Strategies

H Han, HA Santos - Advanced Materials, 2024 - Wiley Online Library
Proteins have emerged as promising therapeutics in oncology due to their great specificity.
Many treatment strategies are developed based on protein biologics, such as …

Injectable responsive chemodynamic hydrogel for the sustained and localized delivery of a ferroptosis inducer to improve anticancer therapy

CH Chung, TW Lu, C Lin, CW Lin, FL Mi - Chemical Engineering Journal, 2024 - Elsevier
Ferroptosis is a promising strategy for cancer therapy because of its distinct reaction
mechanism and potential for overcoming cancer drug resistance. However, the efficient …

Enhancing localized chemotherapy with anti-angiogenesis and nanomedicine synergy for improved tumor penetration in well-vascularized tumors

M Souri, S Elahi, F Moradi Kashkooli… - npj Systems Biology …, 2024 - nature.com
Intratumoral delivery and localized chemotherapy have demonstrated promise in tumor
treatment; however, the rapid drainage of therapeutic agents from well-vascularized tumors …

[HTML][HTML] Redox/NIR dual-responsive glutathione extended polyurethane urea electrospun membranes for synergistic chemo-photothermal therapy

A Martorana, G Puleo, GC Miceli, F Cancilla… - International Journal of …, 2025 - Elsevier
Despite advancements in cancer treatments, therapies frequently exhibit high cytotoxicity,
and surgery remains the predominant method for treating most solid tumors, often with …

[HTML][HTML] Alternative Strategies for Delivering Immunotherapeutics Targeting the PD-1/PD-L1 Immune Checkpoint in Cancer

R Hoshi, KA Gorospe, HI Labouta, T Azad, WL Lee… - Pharmaceutics, 2024 - mdpi.com
The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immune checkpoint
constitutes an inhibitory pathway best known for its regulation of cluster of differentiation 8 …

[HTML][HTML] Prostate cancer chemotherapy by intratumoral administration of Docetaxel-Mesoporous silica nanomedicines

E Rivero-Buceta, A Bernal-Gómez… - International Journal of …, 2024 - Elsevier
Docetaxel (DTX) is a recommended treatment in patients with metastasic prostate cancer
(PCa), despite its therapeutic efficacy is limited by strong systemic toxicity. However, in …

[HTML][HTML] Multivalent ionizable lipid-polypeptides for tumor-confined mRNA transfection

X Zhao, Y Zhang, X Wang, Z Fu, Z Zhong, C Deng - Bioactive Materials, 2025 - Elsevier
Abstract mRNA therapeutics is revolutionizing the treatment concepts toward many diseases
including cancer. The potential of mRNA is, however, frequently limited by modest control …