Background Physical, chemical, and biological factors in the environment constantly
influence in vivo and in vitro biological processes, including diverse histone modifications …

Human male reproductive development has a prolonged prepubertal period characterized
by juvenile quiescence of germ cells with immature spermatogonial stem cell (SSC) …

Spermatogenesis is a multifaceted and meticulously orchestrated process involving meiosis,
chromatin build up, transcriptional and translational hushing, and spermiogenesis. Male …

Little is known of the fundamental processes governed by epigenetic mechanisms in the
supplier cells of spermatogenesis, the spermatogonial stem cells (SSCs). The histone H3 …

The proper regulation of spermatogenesis is crucial to ensure the continued production of
sperm and fertility. Here, we investigated the function of the H3K4me2 demethylase …

Abstract Objectives Acrolein (Acr) is a highly reactive α, β‐unsaturated aldehyde, which can
induce reactive oxygen species (ROS) generation. Several factors, including lipid …

Contents The aim of the study was to screen the entire bull genome to identify markers and
candidate genes underlying sperm concentration. The analysed data set originates from a …

The formation of sperm requires tightly regulated gene expression and unique chromatin
remodeling. In the present study, we investigated the spermatogenic distribution of the lysine …

Objectives: Mesenchymal stem cells are expected to be an ideal cell source for cellular and
gene therapy. We previously showed that cells derived from the human placenta can be …

Objective Epigenetic and genetic changes have important roles in stem cell achievements.
Accordingly, the aim of this study is the evaluation of the epigenetic and genetic alterations …