Sugar serves as the primary energy source for mammals, with glucose metabolism
facilitating energy acquisition in human cells. The proper functioning of intracellular glucose …

CD24 is a glycosylphosphatidylinositol-anchored protein that is expressed in a wide range
of tissues and cell types. It is involved in a variety of physiological and pathological …

Abstract Background Approximately 20–50% of patients presenting with localized colorectal
cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is …

Simple Summary Hyper-angiogenesis is a characteristic of glioblastoma (GBM), and anti-
angio-genesis is a crucial strategy to interfere with tumor progression in GBM therapy. We …

Temozolomide (TMZ) is standard treatment for glioblastoma (GBM); nonetheless, resistance
and tumor recurrence are still major problems. In addition to its association with recurrent …

Aldehyde dehydrogenases (ALDHs) are a family of enzymes that aid in detoxification and
are overexpressed in several different malignancies. There is a correlation between …

Aldehyde dehydrogenase 1A3 (ALDH1A3), one of the three members of the aldehyde
dehydrogenase 1A subfamily, has been associated with increased progression and drug …

Anticancer drug-tolerant persister (DTP) cells at an early phase of chemotherapy reshape
refractory tumors. Aldehyde dehydrogenase 1 family member A3 (ALDH1A3) is commonly …

Background Basal-like breast cancer originates in luminal progenitors, frequently with an
altered PI3K pathway, and focally in close association with genetically altered myoepithelial …

The liver is an immune-tolerant organ, allowing for organ transplantation with less immune
suppression compared with other organs. It also provides fertile soil for tumor metastases …