Background The addition of trabectedin to doxorubicin, followed by trabectedin
maintenance, may have superior efficacy to doxorubicin alone as first-line treatment in …

Sarcoma subtype classification is currently mainly based upon histopathological
morphology. Molecular analyses have emerged as an efficient addition to the diagnostic …

Objective The objective was to review the pharmacology, efficacy, and safety of
atezolizumab (Tecentriq) for the treatment of adult and pediatric patients aged 2 years and …

Epithelioid hemangioendothelioma: a nationwide study Epithelioid hemangioendothelioma
(EHE) is an ultrarare sarcoma whose natural history and treatment is not well defined. We …

Prognostic value of hematologic indices and their association with the tumor
microenvironment (TME) remain unclear in advanced soft tissue sarcoma (STS). We aimed …

Increasing awareness of gonadotoxicity in cancer treatments and infertility risk is essential
for counseling young cancer patients. While fertility preservation options are available in …

BACKGROUND. Treatment options are limited in patients with recurrent or metastatic
disease after initial treatment of soft-tissue sarcoma (STS) by surgical resection, radiation, or …

Opinion Statement Myxoid/round-cell liposarcoma (MRCL) account for 30% of liposarcomas
and are the most chemo-sensitive subtype of liposarcoma. The 5-year local relapse and …

Sarcomas are rare malignancies with over 100 distinct histological subtypes. Their rarity and
heterogeneity pose significant challenges to identifying effective therapies, and approved …

Simple Summary Soft tissue sarcomas represent a large heterogeneous group of malignant
neoplasms that are characterized by a poor disease outcome and being poorly studied …