Pacemaker Channels and the Chronotropic Response in Health and Disease

K Hennis, C Piantoni, M Biel, S Fenske… - Circulation …, 2024 - Am Heart Assoc
Loss or dysregulation of the normally precise control of heart rate via the autonomic nervous
system plays a critical role during the development and progression of cardiovascular …

cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement

L Mu, X Liu, H Yu, CR Vickstrom, V Friedman… - Molecular …, 2023 - nature.com
Chronic cocaine exposure induces enduring neuroadaptations that facilitate motivated drug
taking. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to …

A Molecular framework for delirium

KA Lyman - The Neurohospitalist, 2024 - journals.sagepub.com
Over 2.6 million adults over the age of 65 develop delirium each year in the United States
(US). Delirium is associated with a significant increase in mortality and the US health care …

Characterization of hyperpolarization-activated cyclic nucleotide-gated channels in oligodendrocytes

KA Lyman, Y Han, AP Robinson… - Frontiers in Cellular …, 2024 - frontiersin.org
Mature oligodendrocytes (OLG) are the myelin-forming cells of the central nervous system.
Recent work has shown a dynamic role for these cells in the plasticity of neural circuits …