Basics of the virology of HIV-1 and its replication

S Sierra, B Kupfer, R Kaiser - Journal of clinical virology, 2005 - Elsevier
Human immunodeficiency virus is undoubtedly the causative agent of AIDS. The
understanding of HIV-1 pathogenesis is essentiell to develop and maintain antiretroviral …

Human antibodies from combinatorial libraries

DR Burton, CF Barbas III - Advances in Immunology, 1994 - Elsevier
Publisher Summary Combinatorial antibodies will play a significant role in the design of
vaccines and new antiviral agents. Antibodies may also provide a way of determining …

Secretory leukocyte protease inhibitor: a human saliva protein exhibiting anti-human immunodeficiency virus 1 activity in vitro.

TB McNeely, M Dealy, DJ Dripps… - The Journal of …, 1995 - Am Soc Clin Investig
Infection of adherent primary monocytes with HIV-1Ba-L is significantly suppressed in the
presence of human saliva. By reverse transcriptase (RT) levels, saliva, although present for …

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human …

P Roben, JP Moore, M Thali, J Sodroski… - Journal of …, 1994 - Am Soc Microbiol
Six recombinant human Fab fragments that were derived from the same human
immunodeficiency virus type 1 (HIV-1)-infected individual and are directed against the CD4 …

V3: HIV's switch-hitter

O Hartley, PJ Klasse, QJ Sattentau… - AIDS Research & Human …, 2005 - liebertpub.com
The third variable region, V3, of the gp120 surface envelope glycoprotein is an
approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded …

Maturation of HIV envelope glycoprotein precursors by cellular endoproteases

M Moulard, E Decroly - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2000 - Elsevier
The entry of enveloped viruses into its host cells is a crucial step for the propagation of viral
infection. The envelope glycoprotein complex controls viral tropism and promotes the …

Genetic differences between blood-and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements …

BT Korber, KJ Kunstman, BK Patterson… - Journal of …, 1994 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) sequences were generated from blood and
from brain tissue obtained by stereotactic biopsy from six patients undergoing a diagnostic …

Inhibition of human immunodeficiency virus type 1 infectivity by secretory leukocyte protease inhibitor occurs prior to viral reverse transcription

TB McNeely, DC Shugars, M Rosendahl… - Blood, The Journal …, 1997 - ashpublications.org
Infection of monocytes with human immunodeficiency virus type 1Ba-L (HIV-1Ba-L) is
significantly inhibited by treatment with the serine protease inhibitor, secretory leukocyte …

Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells.

JF Mayaux, A Bousseau, R Pauwels… - Proceedings of the …, 1994 - National Acad Sciences
A series of triterpene compounds characterized by a stringent structure-activity relationship
were identified as potent and selective inhibitors of human immunodeficiency virus type 1 …

Cellular receptors and viral glycoproteins involved in retrovirus entry

RA Weiss - The retroviridae, 1993 - Springer
The initial steps in virus infection involve the binding of virions to specific cell surface
receptors. Following the attachment of enveloped viruses, further events lead to membrane …