Challenges in recombinant brain-derived neurotrophic factor production
Brain-derived neurotrophic factor (BDNF) is a neurotrophin of marked commercial, scientific,
diagnostic, and therapeutic interest. The preservation of its structural cystine-knot is the main …
diagnostic, and therapeutic interest. The preservation of its structural cystine-knot is the main …
Pro region engineering of nerve growth factor by deep mutational scanning enables a yeast platform for conformational epitope mapping of anti‐NGF monoclonal …
AV Medina‐Cucurella, Y Zhu, SJ Bowen… - Biotechnology and …, 2018 - Wiley Online Library
Nerve growth factor (NGF) plays a central role in multiple chronic pain conditions. As such,
anti‐NGF monoclonal antibodies (mAbs) that function by antagonizing NGF downstream …
anti‐NGF monoclonal antibodies (mAbs) that function by antagonizing NGF downstream …
Identification of brain ECM binding variable lymphocyte receptors using yeast surface display
Extracellular matrix (ECM) is a rich mixture of proteins and glycans secreted by cells. This
includes typical ECM structures such as collagen and heparin as well as glycosylated …
includes typical ECM structures such as collagen and heparin as well as glycosylated …
Use of Brevibacillus choshinensis for the production of biologically active brain-derived neurotrophic factor (BDNF)
PA Angart, RJ Carlson, S Thorwall… - Applied microbiology and …, 2017 - Springer
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family critical for
neuronal cell survival and differentiation, with therapeutic potential for the treatment of …
neuronal cell survival and differentiation, with therapeutic potential for the treatment of …
[图书][B] Engineering Deep Sequencing-Guided Platforms to Evaluate Sequence-Function Relationships between Proteins for the Development of Therapeutic …
AV Medina-Cucurella - 2019 - search.proquest.com
Over the past two decades, monoclonal antibodies (mAbs) have been used as a major class
of therapeutic treatments for cancer and autoimmune diseases given their high specificity …
of therapeutic treatments for cancer and autoimmune diseases given their high specificity …
Enzyme Evolution
N Miura - … Cell Surface Engineering: Biological Mechanisms and …, 2019 - Springer
In this chapter, we discuss how to obtain enzymes with desired functions by using yeast cell
surface display methods. Although useful enzymes can be found in natural environments …
surface display methods. Although useful enzymes can be found in natural environments …