Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism

GA Dienel, NF Cruz - Journal of neurochemistry, 2016 - Wiley Online Library
Aerobic glycolysis occurs during brain activation and is characterized by preferential up‐
regulation of glucose utilization compared with oxygen consumption even though oxygen …

A gut-derived metabolite alters brain activity and anxiety behaviour in mice

BD Needham, M Funabashi, MD Adame, Z Wang… - Nature, 2022 - nature.com
Integration of sensory and molecular inputs from the environment shapes animal behaviour.
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …

The epileptic network and cognition: What functional connectivity is teaching us about the childhood epilepsies

JJ Bear, KE Chapman, JR Tregellas - Epilepsia, 2019 - Wiley Online Library
Our objective was to summarize and evaluate the rapidly expanding body of literature
studying functional connectivity in childhood epilepsy. In the self‐limited childhood …

Pregabalin alleviates anxiety and fear in cats during transportation and veterinary visits—a clinical field study

T Lamminen, M Korpivaara, J Aspegrén, C Palestrini… - Animals, 2023 - mdpi.com
Simple Summary Cats are often anxious during travel and veterinary visits which can lead to
a lack of veterinary care. In this study, a novel pregabalin 50 mg/mL oral solution was tested …

Efficacy of a single dose of pregabalin on signs of anxiety in cats during transportation—a pilot study

T Lamminen, M Korpivaara, M Suokko… - Frontiers in Veterinary …, 2021 - frontiersin.org
Objectives: The aim of this clinical pilot study was to evaluate the dosage, efficacy, and
clinical safety of a single oral dose of pregabalin in cats that experience fear and anxiety …

Exercise alters resting-state functional connectivity of motor circuits in parkinsonian rats

Z Wang, Y Guo, KG Myers, R Heintz, YH Peng… - Neurobiology of …, 2015 - Elsevier
Few studies have examined changes in functional connectivity after long-term aerobic
exercise. We examined the effects of 4 weeks of forced running wheel exercise on the …

[HTML][HTML] Juvenile myoclonic epilepsy has hyper dynamic functional connectivity in the dorsolateral frontal cortex

Y Wang, IS Berglund, M Uppman, TQ Li - NeuroImage: Clinical, 2019 - Elsevier
Purpose Characterize the static and dynamic functional connectivity for subjects with
juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach …

Pharmacokinetics of single and repeated oral doses of pregabalin oral solution formulation in cats

T Lamminen, A Doedée… - Journal of Veterinary …, 2022 - Wiley Online Library
The study was designed to determine the pharmacokinetic profile and bioavailability of a
novel pregabalin 50 mg/ml oral solution formulation (Bonqat®, Orion Corporation Orion …

Abnormal metabolic connectivity in the pilocarpine-induced epilepsy rat model: a multiscale network analysis based on persistent homology

H Choi, YK Kim, H Kang, H Lee, HJ Im, EE Kim… - Neuroimage, 2014 - Elsevier
Temporal lobe epilepsy is associated with dysfunctional brain networks. Here we
investigated metabolic connectivity in the pilocarpine-induced epilepsy rat model and …

Efficacy and safety of pregabalin in the treatment of alcohol and benzodiazepine dependence

P Oulis, G Konstantakopoulos - Expert Opinion on Investigational …, 2012 - Taylor & Francis
Introduction: Both alcohol and benzodiazepine dependence (AD, BD) are severe and
chronic conditions with devastating physical and mental health effects. The relative scarcity …