Multifunctional polymeric micelle-based nucleic acid delivery: Current advances and future perspectives

I Jarak, M Pereira-Silva, AC Santos, F Veiga… - Applied Materials …, 2021 - Elsevier
Nucleic acid (NA) therapeutics are a rapidly growing class of biomedicines with the ability to
manipulate gene expression in potent and specific manner, and with the enormous potential …

Development and disassembly of single and multiple acid-cleavable block copolymer nanoassemblies for drug delivery

AM Jazani, JK Oh - Polymer Chemistry, 2020 - pubs.rsc.org
Drug delivery via block copolymer nanoassemblies has been widely viewed as an efficient
way to augment therapeutic efficiency of anticancer drugs for cancer therapy. Acid …

PEG-b-PCL Copolymer Micelles with the Ability of pH-Controlled Negative-to-Positive Charge Reversal for Intracellular Delivery of Doxorubicin

H Deng, J Liu, X Zhao, Y Zhang, J Liu, S Xu… - …, 2014 - ACS Publications
The application of PEG-b-PCL micelles was dampened by their inherent low drug-loading
capability and relatively poor cell uptake efficiency. In this study, a series of novel PEG-b …

Nucleic acids based polyelectrolyte complexes: Their complexation mechanism, morphology, and stability

YH Kim, K Lee, S Li - Chemistry of Materials, 2021 - ACS Publications
Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …

Vinyl Polymer-based technologies towards the efficient delivery of chemotherapeutic drugs

P Pereira, AC Serra, JFJ Coelho - Progress in Polymer Science, 2021 - Elsevier
The application of synthetic polymers as delivery systems of chemotherapy drugs has
opened a very prospective field for research in cancer therapy. Due to their unique and …

Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity

J Shi, B Ma, Y Zhang, H Yong, Z Li, X Huang… - Chemistry of …, 2023 - ACS Publications
Cancer therapy is a global biomedical challenge, and a number of promising anticancer
therapeutics, such as small-molecule drugs, proteins, nucleic acids, photothermal agents …

Recent advances in the application of ATRP in the synthesis of drug delivery systems

M Szewczyk-Łagodzińska, A Plichta, M Dębowski… - Polymers, 2023 - mdpi.com
Advances in atom transfer radical polymerization (ATRP) have enabled the precise design
and preparation of nanostructured polymeric materials for a variety of biomedical …

End‐/side‐chain fluorescent polymer conjugates: Stimuli‐responsiveness and biological applications

M Kar, TK Mandal - Journal of Polymer Science, 2024 - Wiley Online Library
Smart fluorescent polymers are an interesting class of advanced materials that find
widespread applications in diverse areas ranging from materials chemistry to biology. This …

Current status of ATRP-based materials for gene therapy

S de Ávila Gonçalves, RP Vieira - Reactive and Functional Polymers, 2020 - Elsevier
Gene therapy is an auspicious alternative to treat diseases. However, the design of efficient
vectors remains as a challenge due to the innumerous intracellular and extracellular barriers …

Rheological influence of short-chain branching for polymeric materials under shear with variable branch density and branching architecture

SH Jeong, JM Kim, C Baig - Macromolecules, 2017 - ACS Publications
An important objective in polymer science is to manipulate the material properties of
polymers by altering their molecular architecture. To this end, understanding of the …