Spaceflight-induced intracranial hypertension and visual impairment: pathophysiology and countermeasures
LF Zhang, AR Hargens - Physiological reviews, 2018 - journals.physiology.org
Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …
[HTML][HTML] Neurovascular dysfunction in glaucoma
L Alarcon-Martinez, Y Shiga… - Progress in Retinal and …, 2023 - Elsevier
Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …
Age-related alterations in the retinal microvasculature, microcirculation, and microstructure
Purpose: To characterize age-related alterations in the retinal microcirculation,
microvascular network, and microstructure in healthy subjects. Methods: Seventy-four …
microvascular network, and microstructure in healthy subjects. Methods: Seventy-four …
Optical coherence tomography angiography vessel density in glaucomatous eyes with focal lamina cribrosa defects
Purpose To investigate whether vessel density assessed by optical coherence tomography
angiography (OCT-A) is reduced in glaucomatous eyes with focal lamina cribrosa (LC) …
angiography (OCT-A) is reduced in glaucomatous eyes with focal lamina cribrosa (LC) …
[HTML][HTML] The relationship between intraocular pressure and glaucoma: An evolving concept
Intraocular pressure (IOP) is the most important modifiable risk factor for glaucoma and
fluctuates considerably within patients over short and long time periods. Our field's …
fluctuates considerably within patients over short and long time periods. Our field's …
Autoregulation and neurovascular coupling in the optic nerve head
Impairments of autoregulation and neurovascular coupling in the optic nerve head play a
critical role in ocular pathologies, especially glaucomatous optic neuropathy. We critically …
critical role in ocular pathologies, especially glaucomatous optic neuropathy. We critically …
Ocular blood flow as a clinical observation: Value, limitations and data analysis
Alterations in ocular blood flow have been identified as important risk factors for the onset
and progression of numerous diseases of the eye. In particular, several population-based …
and progression of numerous diseases of the eye. In particular, several population-based …
[HTML][HTML] Cerebrospinal fluid pressure: revisiting factors influencing optic nerve head biomechanics
Purpose: To model the sensitivity of the optic nerve head (ONH) biomechanical environment
to acute variations in IOP, cerebrospinal fluid pressure (CSFP), and central retinal artery …
to acute variations in IOP, cerebrospinal fluid pressure (CSFP), and central retinal artery …
Neurodegenerative disorders of the eye and of the brain: a perspective on their fluid-dynamical connections and the potential of mechanism-driven modeling
Neurodegenerative disorders (NDD) such as Alzheimer's and Parkinson's diseases are
significant causes of morbidity and mortality worldwide. The pathophysiology of NDD is still …
significant causes of morbidity and mortality worldwide. The pathophysiology of NDD is still …
[HTML][HTML] No flow through the vitreous humor: How strong is the evidence?
When analyzing vitreal drug delivery, or the pharmacological effects of drugs on intraocular
pressure, or when interpreting outflow facility measurements, it is generally accepted that the …
pressure, or when interpreting outflow facility measurements, it is generally accepted that the …