Ethnopharmacological relevance Propolis is a natural product produced by honeybees used
as a medicine at least to 300 BC. In the last decades, several studies showed biological and …

The protective effects of mycobacterial infections on lung allergy are well documented.
However, the inverse relationship between tuberculosis and type 2 immunity is still elusive …

Eosinophilic, noneosinophilic, or mixed granulocytic inflammations are the hallmarks of
asthma heterogeneity. Depending on the priming of lung immune and structural cells …

Changing the immune responses to allergens is the cornerstone of allergen immunotherapy.
Allergen-specific immunotherapy that consists of repeated administration of increasing …

Abstract Interleukin-35 (IL-35) is a novel anti-inflammatory cytokine and has been shown to
play an important role in maintaining immune homeostasis. However, the effect of IL-35 on …

Allergic rhinitis (AR) is a common disease that requires more convenient, safe and effective
antigen‑specific immunotherapies. The present study aimed to investigate the therapeutic …

Allergic asthma is an inflammatory disorder characterized by infiltration of the airway wall
with inflammatory cells driven mostly by activation of Th2-lymphocytes, eosinophils and mast …

There is evidence that IL-22 and IL-17 participate in the pathogenesis of allergic asthma. To
investigate the role of IL-22, we used IL-22 deficient mice (IL-22 KO) sensitized and …

Background Allergic asthma is a chronic pulmonary disease characterized by a Th2
inflammatory response. The modulation of a Th2 immune response based on immune …

Background We have shown that mycobacterial antigens and CpG oligodeoxynucleotides
downmodulate airway allergic inflammation by mechanisms dependent on T‐cell activation …