Aims Nephrotoxicity is the hallmark of anti-neoplastic drug metabolism that causes oxidative
stress. External chemical agents and prescription drugs release copious amounts of free …

Mitochondria decay with age due to the oxidation of lipids, proteins, RNA, and DNA. Some of
this decay can be reversed in aged animals by feeding them the mitochondrial metabolites …

As major components of neuronal membranes, omega-3 polyunsaturated acids (n-3 PUFA)
exhibit a wide range of regulatory functions, modulating from synaptic plasticity to …

In this study, the effect of Chrysin (5, 7-dihydroxyflavone), an important member of the
flavonoid family, on memory impairment, oxidative stress and BDNF reduction generated by …

Oxidative stress has been shown to underlie neuropathological aspects of Alzheimer's
disease (AD). 4-Hydroxy-2-nonenal (HNE) is a highly reactive product of lipid peroxidation …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by loss
of memory and cognition and by senile plaques and neurofibrillary tangles in brain. Amyloid …

Oxidative stress may play a key role in Alzheimer's disease (AD) neuropathology.
Pomegranates (石榴 Shí Liú) contain very high levels of antioxidant polyphenolic …

Oxidative mitochondrial decay is a major contributor to aging. Some of this decay can be
reversed in old rats by feeding them normal mitochondrial metabolites, acetylcarnitine (ALC) …

Alzheimer disease (AD) is characterized by dementia that begins as mild short term memory
deficit and culminates in total loss of cognitive and executive functions. The present study …

A rat dementia model with cognitive deficits was generated by synapse‐specific lesions
using botulinum neurotoxin (BoNTx) type B in the entorhinal cortex. To detect cognitive …