The advent of highly successful reperfusion provides the opportunity to consider novel
approaches to cytoprotection as adjunctive therapies. Several therapeutic targets for …

Lacunar stroke is a marker of cerebral small vessel disease and accounts for up to 25% of
ischaemic stroke. In this narrative review, we provide an overview of potential lacunar stroke …

Background and Purpose—Early use of antiplatelet drugs within 24 hours after intravenous
thrombolysis (IVT) has always been a confusing clinical problem. The purpose of this study …

Importance Neurological worsening and recurrent stroke contribute substantially to morbidity
associated with transient ischemic attacks and strokes (TIA-S). Objective To determine …

Objective To improve epidemiologic knowledge of neurologic deterioration (ND) in patients
with acute ischemic stroke (AIS). Methods In this prospective observational study, we …

Objectives A significant proportion of patients with acute minor stroke have unfavorable
functional outcome due to early neurological deterioration (END). The purpose of this study …

Background and Purpose—The relationship between high plasma 20-
hydroxyeicosatetraenoic acid (20-HETE) levels and neurological deterioration (ND) has not …

Objectives: Differentiate lacunar strokes from other types of strokes. Apply evidence-based
interventions for the management of lacunar strokes. Select appropriate diagnostic studies …

Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke aims
to restore compromised blood flow and prevent further neuronal damage. Despite the …

Objectives The mechanisms of early neurologic deterioration (END) and prevention
strategies for END are not completely understood. The aim of this study was to investigate …