Perturbed diurnal rhythms are becoming increasingly evident as deleterious events in the
pathology of metabolic diseases. Exercise is well characterized as a crucial intervention in …

The molecular circadian clock regulates metabolic processes within the cell, and the
alignment of these clocks between tissues is essential for the maintenance of metabolic …

Most bodily functions vary over the course of a 24 h day. Circadian rhythms in body
temperature, sleep-wake cycles, metabolism, and blood pressure (BP) are just a few …

The circadian clock and feeding rhythms are both important regulators of rhythmic gene
expression in the liver. To further dissect the respective contributions of feeding and the …

Numerous physiological functions exhibit substantial circadian oscillations. In the kidneys,
renal plasma flow, the glomerular filtration rate and tubular reabsorption and/or secretion …

Parkinson's disease (PD) is a complex, multisystem disorder with both neurologic and
systemic manifestations, which is usually associated with non-motor symptoms, including …

The circadian timing system is a complex biological network of interacting circadian clocks
that regulates 24 h rhythms of behavioral and physiological processes. One intriguing …

RNA polymerase (Pol) III has a specialized role in transcribing the most abundant RNAs in
eukaryotic cells, transfer RNAs (tRNAs), along with other ubiquitous small noncoding RNAs …

Parkinson's disease (PD) is one of the main neurodegenerative disease characterized by a
progressive degeneration of neurons constituted by dopamine in the substantia nigra pars …

Introduction Most mammalian physiology is orchestrated by the circadian clock, including
drug transport and metabolism. As a result, efficacy and toxicity of many drugs are …