Natural products as modulators of Nrf2 signaling pathway in neuroprotection

I Moratilla-Rivera, M Sánchez… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …

Neuroprotective potential of limonene and limonene containing natural products

LB Eddin, NK Jha, MFN Meeran, KK Kesari, R Beiram… - Molecules, 2021 - mdpi.com
Limonene is a monoterpene confined to the family of Rutaceae, showing several biological
properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and …

[HTML][HTML] Plant-derived terpenoids: A plethora of bioactive compounds with several health functions and industrial applications—A comprehensive overview

JS Câmara, R Perestrelo, R Ferreira, CV Berenguer… - Molecules, 2024 - mdpi.com
Terpenoids are a large class of natural secondary plant metabolites which are highly diverse
in structure, formed from isoprene units (C-5), associated with a wide range of biological …

Valorization of bioactive compounds from juice industry waste: Applications, challenges, and future prospects

AC Pedro, GM Maciel, NP Lima, NF Lima… - Trends in Food Science …, 2024 - Elsevier
Background The juice industry generates substantial volumes of waste annually, including
peels, seeds, and pulp. These by-products present environmental challenges such as …

A triterpenoid lupeol as an antioxidant and anti-neuroinflammatory agent: impacts on oxidative stress in Alzheimer's disease

JS Park, IU Rehman, K Choe, R Ahmad, HJ Lee… - Nutrients, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease illustrated by
neuronal dysfunctions, leading to memory weaknesses and personality changes mostly in …

Interaction between dietary fibre and bioactive compounds in plant by-products: Impact on bioaccessibility and bioavailability

V Núñez-Gómez, R González-Barrio, MJ Periago - Antioxidants, 2023 - mdpi.com
In Europe, around 31 million tonnes of food by-products are generated during primary
production and trade. The management of these by-products may cause a negative impact …

Neuroprotective effects of agri-food by-products rich in phenolic compounds

A Rojas-García, Á Fernández-Ochoa, ML Cádiz-Gurrea… - Nutrients, 2023 - mdpi.com
Neurodegenerative diseases are known for their wide range of harmful conditions related to
progressive cell damage, nervous system connections and neuronal death. These …

[HTML][HTML] Development of a sustainable extraction and storage stability of antioxidant and anticholinergic pressurized natural deep eutectic solvent extracts from Citrus …

G Domínguez-Rodríguez, VM Amador-Luna… - Food and Bioproducts …, 2025 - Elsevier
The recovery of phenolic compounds from C. reticulata leaves using pressurized liquid
extraction (PLE) combined with Natural Deep Eutectic Solvents (NaDES) employing Choline …

[HTML][HTML] Anti-inflammatory and neuroprotective evaluation of diverse microalgae extracts enriched in carotenoids

R Gallego, A Valdés, ZJ Suárez-Montenegro… - Algal Research, 2022 - Elsevier
Microalgae represent one of the most promising sources of bioactive compounds for the
pharmaceutical and food industries. Among these bioactives, carotenoids could be …

Nootkatone alleviates rotenone‐induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway

Z Yao, J Li, L Bian, Q Li, X Wang, X Yang… - Phytotherapy …, 2022 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Nootkatone (NKT) has been shown to have neuroprotective, anti‐inflammatory …