Understanding the role of puberty in structural and functional development of the adolescent brain
AL Goddings, A Beltz, JS Peper… - Journal of Research …, 2019 - Wiley Online Library
Over the past two decades, there has been a tremendous increase in our understanding of
structural and functional brain development in adolescence. However, understanding the …
structural and functional brain development in adolescence. However, understanding the …
[HTML][HTML] Axonal transport defects and neurodegeneration: molecular mechanisms and therapeutic implications
Because of the extremely polarized morphology, the proper functioning of neurons largely
relies on the efficient cargo transport along the axon. Axonal transport defects have been …
relies on the efficient cargo transport along the axon. Axonal transport defects have been …
Annual Research Review: Neural contributions to risk‐taking in adolescence–developmental changes and individual differences
EA Crone, ACK van Duijvenvoorde… - Journal of child …, 2016 - Wiley Online Library
Background Risk‐taking, which involves voluntary choices for behaviors where outcomes
remain uncertain, undergoes considerable developmental changes during childhood …
remain uncertain, undergoes considerable developmental changes during childhood …
Early cannabis use, polygenic risk score for schizophrenia and brain maturation in adolescence
Importance Cannabis use during adolescence is known to increase the risk for
schizophrenia in men. Sex differences in the dynamics of brain maturation during …
schizophrenia in men. Sex differences in the dynamics of brain maturation during …
Promise and pitfalls of g-ratio estimation with MRI
The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …
Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury
JP Dollé, A Jaye, SA Anderson, H Ahmadzadeh… - Experimental …, 2018 - Elsevier
Since traumatic axonal injury (TAI) is implicated as a prominent pathology of concussion, we
examined potential sex differences in axon structure and responses to TAI. Rat and human …
examined potential sex differences in axon structure and responses to TAI. Rat and human …
Adult age differences in subcortical myelin content are consistent with protracted myelination and unrelated to diffusion tensor imaging indices
Post mortem studies suggest protracted myelination of subcortical white matter into the
middle age followed by gradual decline in the late adulthood. To date, however, establishing …
middle age followed by gradual decline in the late adulthood. To date, however, establishing …
Evaluating g-ratio weighted changes in the corpus callosum as a function of age and sex
Recent years have seen a growing interest in relating MRI measurements to the structural-
biophysical properties of white matter fibers. The fiber g-ratio, defined as the ratio between …
biophysical properties of white matter fibers. The fiber g-ratio, defined as the ratio between …
Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability
Most mammalian neurons have a narrow axon, which constrains the passage of large
cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal …
cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal …
[HTML][HTML] Mapping an index of the myelin g-ratio in infants using magnetic resonance imaging
Optimal myelination of neuronal axons is essential for effective brain and cognitive function.
The ratio of the axon diameter to the outer fiber diameter, known as the g-ratio, is a reliable …
The ratio of the axon diameter to the outer fiber diameter, known as the g-ratio, is a reliable …