A unifying perspective on neural manifolds and circuits for cognition

C Langdon, M Genkin, TA Engel - Nature Reviews Neuroscience, 2023 - nature.com
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …

Reconstructing computational system dynamics from neural data with recurrent neural networks

D Durstewitz, G Koppe, MI Thurm - Nature Reviews Neuroscience, 2023 - nature.com
Computational models in neuroscience usually take the form of systems of differential
equations. The behaviour of such systems is the subject of dynamical systems theory …

Imaging whole-brain activity to understand behaviour

A Lin, D Witvliet, L Hernandez-Nunez… - Nature Reviews …, 2022 - nature.com
Until now, most brain studies have focused on small numbers of neurons that interact in
limited circuits, allowing analysis of individual computations or steps of neural processing …

Characterization of regional differences in resting-state fMRI with a data-driven network model of brain dynamics

V Sip, M Hashemi, T Dickscheid, K Amunts… - Science …, 2023 - science.org
Model-based data analysis of whole-brain dynamics links the observed data to model
parameters in a network of neural masses. Recently, studies focused on the role of regional …

Dynamics on the manifold: Identifying computational dynamical activity from neural population recordings

L Duncker, M Sahani - Current opinion in neurobiology, 2021 - Elsevier
The question of how the collective activity of neural populations gives rise to complex
behaviour is fundamental to neuroscience. At the core of this question lie considerations …

Learning identifiable and interpretable latent models of high-dimensional neural activity using pi-VAE

D Zhou, XX Wei - Advances in Neural Information …, 2020 - proceedings.neurips.cc
The ability to record activities from hundreds of neurons simultaneously in the brain has
placed an increasing demand for developing appropriate statistical techniques to analyze …

Extracting computational mechanisms from neural data using low-rank RNNs

A Valente, JW Pillow, S Ostojic - Advances in Neural …, 2022 - proceedings.neurips.cc
An influential framework within systems neuroscience posits that neural computations can
be understood in terms of low-dimensional dynamics in recurrent circuits. A number of …

Metastable dynamics of neural circuits and networks

BAW Brinkman, H Yan, A Maffei, IM Park… - Applied Physics …, 2022 - pubs.aip.org
Cortical neurons emit seemingly erratic trains of action potentials or “spikes,” and neural
network dynamics emerge from the coordinated spiking activity within neural circuits. These …

Inferring latent dynamics underlying neural population activity via neural differential equations

TD Kim, TZ Luo, JW Pillow… - … Conference on Machine …, 2021 - proceedings.mlr.press
An important problem in systems neuroscience is to identify the latent dynamics underlying
neural population activity. Here we address this problem by introducing a low-dimensional …

A general recurrent state space framework for modeling neural dynamics during decision-making

D Zoltowski, J Pillow… - … Conference on Machine …, 2020 - proceedings.mlr.press
An open question in systems and computational neuroscience is how neural circuits
accumulate evidence towards a decision. Fitting models of decision-making theory to neural …