An update on the management of breast cancer in Africa

V Vanderpuye, S Grover, N Hammad… - Infectious agents and …, 2017 - Springer
Background There is limited information about the challenges of cancer management and
attempts at improving outcomes in Africa. Even though South and North Africa are better …

Global inequities in precision medicine and molecular cancer research

TM Drake, SR Knight, EM Harrison, K Søreide - Frontiers in Oncology, 2018 - frontiersin.org
Precision medicine based upon molecular testing is heralded as a revolution in how cancer
is prevented, diagnosed, and treated. Large efforts across the world aim to conduct …

A review on breast cancer care in Africa

EJ Kantelhardt, G Muluken, G Sefonias, A Wondimu… - Breast Care, 2015 - karger.com
Background: The global incidence of breast cancer (BC) is rising, especially in low-and
middle-income countries. The purpose of this review is to summarize existing publications …

Building capacity for sustainable research programmes for cancer in Africa

I Adewole, DN Martin, MJ Williams… - Nature reviews Clinical …, 2014 - nature.com
Cancer research in Africa will have a pivotal role in cancer control planning in this continent.
However, environments (such as those in academic or clinical settings) with limited research …

Implementing oncology clinical trials in Nigeria: a model for capacity building

A Ntekim, A Ibraheem, A Adeniyi-Sofoluwe… - BMC Health Services …, 2020 - Springer
Background There is both higher mortality and morbidity from cancer in low and medium
income countries (LMICs) compared with high income countries (HICs). Clinical trial …

Pharmacogenetics of breast cancer treatments: a sub-Saharan Africa perspective

KC Nthontho, AK Ndlovu, K Sharma… - Pharmacogenomics …, 2022 - Taylor & Francis
Breast cancer is the most frequent cause of cancer death in low-and middle-income
countries, in particular among sub-Saharan African women, where response to available …

Taking on breast cancer in East Africa: global challenges in breast cancer

EJ Kantelhardt, H Cubasch… - Current Opinion in …, 2015 - journals.lww.com
Breast cancer is an increasing health problem in low-resource countries. More information
on incidence, clinical presentation, outcome, and tumor biology in Africa has become …

A comparison of toxicity profiles between the lower and standard dose capecitabine in breast cancer: a systematic review and meta-analysis

TF Nishijima, M Suzuki, HB Muss - Breast cancer research and treatment, 2016 - Springer
Capecitabine 1000 mg/m 2 bid× 14 days every 21 days (14/21) has been reported to have
similar efficacy but more favorable toxicity profile than the approved dosage of 1250 mg/m 2 …

Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives

N Wright, P Rida, E Rakha, A Agboola… - Journal of global …, 2018 - ascopubs.org
Purpose Triple-negative breast cancer (TNBC) is the most deadly form of breast cancer (BC)
today. TNBC treatment is fraught with challenges because of the extensive interpatient …

Neoadjuvant chemotherapy among patients treated for nonmetastatic breast cancer in a population with a high HIV prevalence in Johannesburg, South Africa

P Ruff, H Cubasch, M Joffe, E Rosenbaum… - Cancer management …, 2018 - Taylor & Francis
Background Neoadjuvant (primary) chemotherapy (NACT) is the standard of care for locally
advanced breast cancer. It also allows for the short-term assessment of chemotherapy …