The emergence of additional chromosomal abnormalities (ACAs) in Philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia (CML), is considered to be a …
A Amouei, N Daeian, SS Khezrnia… - … -Oncology and Stem …, 2021 - ncbi.nlm.nih.gov
Background: Imatinib is the gold standard in the treatment of chronic myeloid leukemia (CML) patients. Resistance to imatinib is interfering with patients' responses and their …
S Benchikh, SSG Charlène, A Bousfiha, L Razoki… - Annals of …, 2024 - Springer
Chronic myeloid leukemia (CML) is a neoplastic disease of genetic origin resulting from clonal proliferation of hematopoietic stem cells (HSCs). The reciprocal translocation t (9; …
BB Ganguly, S Mandal, D Banerjee… - Journal of Cancer …, 2022 - journals.lww.com
Purpose: The chronic myeloid leukemia (CML) is characterized by the presence of t (9; 22)(q34; q11) that results in chimerization of BCR and ABL genes on the rearranged …
A Largo-Peralta, M Rondón-Lagos… - Universitas …, 2023 - biogenetica.com.co
Abstract Chronic Myeloid Leukemia (CML) is characterized by the presence of the Philadelphia (Ph) chromosome, resulting from a translocation between chromosomes 9 and …
Background Acute promyelocytic leukaemia results from reciprocal translocation between the long arms of chromosomes 15 and 17. This translocation leads to the formation of …
Abstract 90% of Chronic Myeloid Leukemia (CML) patients having Philadelphia (Ph) chromosome or t (9; 22)(q34; q11. 2), and the remaining 5–8% of CML patients demonstrate …
KK Abdullah, MF Namik… - The Egyptian Journal of …, 2023 - ejhm.journals.ekb.eg
Background: Metformin, an anti-hyperglycemic drug, treats type 2 diabetes with diet. It increases muscle glucose consumption, maintains blood levels, and does not cause severe …
NAR Jaleil, WM Abed - Medical Journal of Babylon, 2021 - journals.lww.com
Background: Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm that is characterized by the presence of the Philadelphia (Ph) chromosome, which results from a …