The role of free radicals in various human ailments is well established. Still, the researchers
continue to emphasize the involvement of free radicals in these disorders. Antioxidants are …

Numerous studies have shown that oxidative stress resulting from an imbalance between
the production of free radicals and their neutralization by antioxidant enzymes is one of the …

The phagocytic cell enzyme NADPH oxidase-2 (Nox2) is critical for killing micro-organisms
via production of reactive oxygen species and thus is a key element of the innate immune …

JCI - Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature
Go to JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts …

Senescent cells withdraw from the cell cycle and do not proliferate. The prevalence of
senescent compared to normally functioning parenchymal cells increases with age …

First described as essential to the phagocytic activity of leukocytes, Nox2-derived ROS have
emerged as mediators of a range of cellular and tissue responses across species from …

Reactive oxygen species (ROS) are widely involved in intracellular signaling and human
pathologies, but their precise roles have been difficult to enumerate and integrate …

NADPH oxidases (NOXs) represent one of the major sources of reactive oxygen species in
the vascular district. Reactive oxygen species are responsible for vascular damage that …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase p22phox subunit
polymorphisms, systemic oxidative stress, endothelia Page 1 ORIGINAL ARTICLE CYBA …

Objective The link between the systemic vasculature system and tumor biology is here
investigated by studying the contribution of CβS (844ins68), MTHFR (677C> T), NOS3 …