Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …

Various diseases and toxic factors easily impair cellular and organic functions in mammals.
Organ transplantation is used to rescue organ function, but is limited by scarce resources …

The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

The regeneration of lost periodontal apparatus in periodontitis treatment remains a clinical
challenge due to the limited regenerative capacity of cementum, periodontal ligament and …

As far as health issues are concerned, cancer causes one out of every six deaths around the
globe. As potent therapeutics are still awaited for the successful treatment of cancer, some …

Adult stem cells ensure tissue homeostasis and regeneration after injury. Due to their
longevity and functional requirements, throughout their life stem cells are subject to a …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint destruction,
synovitis, and pannus formation. Gut microbiota dysbiosis may exert direct pathogenic …

Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as
immunomodulation, fever, inflammatory response, inhibition of tumor formation, and …

Mesenchymal stem cells (MSCs), as cells with potential clinical utilities, have demonstrated
preferential incorporation into inflammation sites. Immunophenotype and …

Abstract Interleukin (IL)-37, a pivotal anti-inflammatory cytokine and a fundamental inhibitor
of innate immunity, has recently been shown to be abnormally expressed in several …