Conspectus α-Diazocarbonyl compounds serve as nucleophiles, dipoles, carbene
precursors, and rare electrophiles, enabling a vast array of organic transformations under …

In 1994, Ye and McKervey published a paper in Chemical Reviews entitled “Organic
Synthesis with α-Diazocarbonyl Compounds”. 1 Our intention then was to draw attention to …

Aliphatic amines strongly coordinate, and therefore easily inhibit, the activity of transition-
metal catalysts, posing a marked challenge to nitrogen-hydrogen (N–H) insertion reactions …

Enoldiazo esters and amides have proven to be versatile reagents for cycloaddition
reactions that allow highly efficient construction of various carbocycles and heterocycles …

Conspectus The combination of two or more unsaturated structural units to form cyclic
organic compounds is commonly referred to as cycloaddition, and the combination of two …

The conversion of inexpensive aqueous ammonia (NH3· H2O) into value-added primary
amines by N− H insertion persists as a longstanding challenge in chemistry because of the …

Transition metal-catalyzed carbene insertion into X–H bonds (X= N, O, S, and C) represents
a typical carbene transfer reaction and has been widely used in organic synthesis. The …

While asymmetric insertion of metal carbenes into H–X (X= C, N, O, etc.) bonds has been
well-established, asymmetric control over free carbenes is challenging due to the presence …

Free carbene readily causes multiple side reactions due to its high energy, thus its
asymmetric transformation is very difficult. We present here our findings of high‐pKa …

C3‐substituted indoles and carbazoles react with α‐aryl‐α‐diazoesters under palladium
catalysis to form α‐(N‐indolyl)‐α‐arylesters and α‐(N‐carbazolyl)‐α‐arylesters. The …