Extracellular purines in lung endothelial permeability and pulmonary diseases

E Gerasimovskaya, RS Patil, A Davies… - Frontiers in …, 2024 - frontiersin.org
The purinergic signaling system is an evolutionarily conserved and critical regulatory circuit
that maintains homeostatic balance across various organ systems and cell types by …

[HTML][HTML] Could P2X7 receptor be a potencial target in neonatal sepsis?

S Fialho, P Trieu-Cuot, P Ferreira, L Oliveira - International …, 2024 - Elsevier
Abstract The United Nations Inter-Agency Group for Child Mortality Estimation (UNIGME)
estimates that every year 2.5 million neonates die in their first month of life, accounting for …

P2X7 receptor: A receptor closely linked with sepsis-associated encephalopathy

Z Fan, K Wang, X Zhao, X Sun - Open Life Sciences, 2024 - degruyter.com
Sepsis is defined as a dysregulated host response to infection resulting in life-threatening
organ dysfunction. Sepsis-associated encephalopathy (SAE) is the main manifestation of …

PAMPs and DAMPs in sepsis: a review of their molecular features and potential clinical implications

S Cicchinelli, G Pignataro, S Gemma… - International Journal of …, 2024 - mdpi.com
Sepsis is a serious organ dysfunction caused by a dysregulated immune host reaction to a
pathogen. The innate immunity is programmed to react immediately to conserved molecules …