Biliary excretion of xenobiotics is a complex process involving uptake into liver cells,
intracellular sequestration and/or biotransformation, and transport into bile. A description of …

Publisher Summary This chapter discusses the metabolism of molecular species of
diacylglycerophospholipids. The glycerolipid composition of cell membranes and …

In this study we have demonstrated that in native bile, lipids are organized in the form of a
lipoprotein (bile LP) carrying albumin as apoprotein. The lipid composition of bile LP is …

The digestion of choline phospholipids is important for choline homeostasis, lipid signaling,
postprandial lipid and energy metabolism, and interaction with intestinal bacteria. The …

Three markers of free radical oxidation of lipids—9 cis, 11 trans isomer of linoleic acid,
conjugated dienes and ultraviolet fluorescence products—were measured in the …

The mechanisms of bile formation at the level of the hepatocyte have been the subject of
intensive research for several decades. These efforts have been hampered, however, by an …

It should be evident from this review of recent investigations that we are still very far from a
consistent description of bile formation, much less a satisfactory understanding …

The hepatocyte is a polarized cell with a distinct basolateral and an apical (bile canalicular)
domain. Transport processes at the two poles of the cell show a high degree of specifi~ ity.' …

One of the most important activities of the liver is the secretion of bile. Bile is both a secretory
and an excretory fluid. Probably its two most important functions being the delivery to the …

Female rats were subjected to total biliary diversion immediately before or 6 h after [3H]
water had been given by vein. When diversion was commenced just before injection of the …