Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control
immune responses, oxidative stress, and defense cell infiltration. Periodontitis is a disease …

The present study investigated the ability of melatonin in reducing metabolic risk factors and
cardiac apoptosis induced by diabetes. Streptozotocin (60 mg/kg, ip) was injected into male …

Background: The present study aims to investigate the effects of systemic melatonin
administration on alveolar bone resorption in experimental periodontitis in rats. Methods …

The aim of the present study was to assess the therapeutic potential of melatonin (Mel) in
diabetic central neuropathy in a rat model of streptozotocin (STZ)-induced diabetes. The rats …

Pancreatic cancer has a high mortality rate due to the absence of early symptoms and
subsequent late diagnosis; additionally, pancreatic cancer has a high resistance to radio …

Alloxan has been widely used to produce experimental diabetes mellitus syndrome. This
study was undertaken to investigate the protective effect against alloxan-induced pancreatic …

Activation of proliferation of Schwann cells is crucial for axonal guidance and successful
nerve regeneration following peripheral nerve injury (PNI). Considering melatonin plays an …

Autoimmune-led challenge resulting in β-cell loss is responsible for the development of type
1 diabetes (T1D). Melatonin, a pineal hormone or sitagliptin, a dipeptidyl peptidase IV (DPP …