Abstract tRNA-derived small RNAs (tsRNAs), including tRNA-derived fragments (tRFs) and
tRNA halves (tiRNAs), are small regulatory RNAs processed from mature tRNAs or …

With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …

Transfer RNA-derived fragments (tRFs) are emerging small noncoding RNAs that, although
commonly altered in cancer, have poorly defined roles in tumorigenesis. Here we show that …

The fragments that derive from transfer RNAs (tRNAs) are an emerging category of
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …

The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

Abstract tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) are small non-coding
RNAs derived from precursor tRNAs or mature tRNAs. Depending on the sources, tRFs can …

Transfer RNAs (tRNAs) were traditionally considered to participate in protein translation.
Recent studies have identified a novel class of small non-coding RNAs (sncRNAs) …

Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules
that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly …

Introduction: Cancer statistics show that recent improvements in cancer management are
only mildly effective in the absence of reliable biomarkers for the detection, diagnosis and …

Quality control (QC) is a critical step in RNA sequencing (RNA-seq). Yet, it is often ignored or
conducted on a limited basis. Here, we present a multi-perspective strategy for QC of RNA …