Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …

Rotaviruses (RVs) are non-enveloped multilayered dsRNA viruses that are major etiologic
agents of diarrheal disease in humans and in the young in a large number of animal …

Rotaviruses (RVs) preferentially replicate in the small intestine and frequently cause severe
diarrheal disease, and the following enteric infection generally induces variable levels of …

Rotaviruses are major causes of acute gastroenteritis in infants and young children
worldwide and also cause disease in the young of many other mammalian and of avian …

Species A rotavirus (RVA) vaccines based on live attenuated viruses are used worldwide in
humans. The recent establishment of a reverse genetics system for rotoviruses (RVs) has …

Rotaviruses are segmented double-stranded RNA viruses with a high frequency of gene
reassortment, and they are a leading cause of global diarrheal deaths in children less than 5 …

Rotavirus, a segmented double-stranded RNA virus of the Reoviridae family, is a primary
cause of acute gastroenteritis in young children. In countries where rotavirus vaccines are …

Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in
infants and the young of many economically important animals. Although vaccines against …

Reverse genetic systems have been used to introduce heterologous sequences into the
rotavirus segmented double-stranded (ds) RNA genome, enabling the generation of …

Rotaviruses represent one of the most successful pathogens in the world, with high
infectivity and efficient transmission between the young of many animal species, including …