In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

[HTML][HTML] The biological pathways of Alzheimer disease: A review

M Calabrò, C Rinaldi, G Santoro, C Crisafulli - AIMS neuroscience, 2021 - ncbi.nlm.nih.gov
Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Mitochondrial dysfunction in neurodegenerative disorders: Potential therapeutic application of mitochondrial transfer to central nervous system-residing cells

FA Bustamante-Barrientos, N Luque-Campos… - Journal of Translational …, 2023 - Springer
Mitochondrial dysfunction is reiteratively involved in the pathogenesis of diverse
neurodegenerative diseases. Current in vitro and in vivo approaches support that …

Taurine as a natural antioxidant: From direct antioxidant effects to protective action in various toxicological models

PF Surai, K Earle-Payne, MT Kidd - Antioxidants, 2021 - mdpi.com
Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

Recent advances in a polydopamine-mediated antimicrobial adhesion system

I Singh, G Dhawan, S Gupta, P Kumar - Frontiers in microbiology, 2021 - frontiersin.org
The drug resistance developed by bacteria during antibiotic treatment has been a call to
action for researchers and scientists across the globe, as bacteria and fungi develop ever …

Reactive oxygen species and organellar signaling

SY Phua, B De Smet, C Remacle… - Journal of …, 2021 - academic.oup.com
The evolution of photosynthesis and its associated metabolic pathways has been crucial to
the successful establishment of plants, but has also challenged plant cells in the form of …

Mitochondrial dysfunction: pathophysiology and mitochondria-targeted drug delivery approaches

T Khan, R Waseem, Z Zehra, A Aiman, P Bhardwaj… - Pharmaceutics, 2022 - mdpi.com
Mitochondria are implicated in a wide range of functions apart from ATP generation, and,
therefore, constitute one of the most important organelles of cell. Since healthy mitochondria …

Oxidative stress in intestinal ischemia-reperfusion

G Li, S Wang, Z Fan - Frontiers in Medicine, 2022 - frontiersin.org
Ischemia-reperfusion (I/R) injury is a manifestation of tissue or organ damage that is
followed by ischemia and exacerbated by the return of blood flow to a previously damaged …

Redox signaling and metabolism in Alzheimer's disease

MI Holubiec, M Gellert… - Frontiers in Aging …, 2022 - frontiersin.org
Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …

Interplay between mitochondrial oxidative disorders and proteostasis in Alzheimer's disease

E Llanos-González, ÁA Henares-Chavarino… - Frontiers in …, 2020 - frontiersin.org
Although the basis of Alzheimer's disease (AD) etiology remains unknown, oxidative stress
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …