Conventional sampling of biological fluids often involves a bulk quantity of samples that are
tedious to collect, deliver and process. Miniaturized sampling approaches have emerged as …

Therapeutic drug monitoring (TDM) relays in the availability of specialized laboratory
assays, usually available in reference centers that are not accessible to all patients. In this …

Nowadays the practice of therapeutic drug monitoring, consisting in the measurement of
drugs concentrations in biological matrices in order to guide possible posological …

Purpose While in the era of precision medicine, the right drug for each patient is selected
based on molecular tumor characteristics, most novel oral targeted anticancer agents are …

Introduction Direct quantification of drug concentrations allows for medication adherence
monitoring (MAM) and therapeutic drug monitoring (TDM). Multiple less invasive methods …

There are few fields of medicine in which the individualisation of medicines is more
important than in the area of oncology. Under‐dosing can have significant ramifications due …

Background Anticancer drugs are notoriously characterized by a low therapeutic index, the
introduction of therapeutic drug monitoring (TDM) in oncologic clinical practice could …

Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) is not yet performed
routinely in the standard care of oncology patients, although it offers a high potential to …

Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) in cancer therapy
offers the potential to improve treatment efficacy while minimizing toxicity. Therefore, a high …

Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) shows significant
potential in guiding personalized anticancer treatment. Dried blood microsampling could be …