Apolipoprotein AI (ApoA-I), the major protein component of high-density lipoproteins (HDL)
is a multifunctional protein, involved in cholesterol traffic and inflammatory and immune …

The COVID-19 pandemic is an unprecedented global challenge, and point-of-care
diagnostic classifiers are urgently required. Here, we present a platform for ultra-high …

In recent years, the relationship between lipid metabolism and tumour immunotherapy has
been thoroughly investigated. An increasing number of studies have shown that abnormal …

Anemia is common in colorectal cancer (CRC) but its relationships with tumor
characteristics, systemic inflammation, and survival have not been well characterized. In this …

Background Lipid metabolism reprogramming is a hallmark for tumor which contributes to
tumorigenesis and progression, but the commonality and difference of lipid metabolism …

Abstract Background Predicting prognosis in Parkinson's disease (PD) has important
implications for individual prognostication and clinical trials design and targeting novel …

Background Cancer cachexia is a complex wasting syndrome affecting patients with
advanced cancer, with systemic inflammation as a key component in pathogenesis. Protein …

Most pancreatic ductal adenocarcinomas (PDACs) are diagnosed at an advanced or
metastatic stage. Metastasis is the one of the major obstacles to prolonging the survival time …

Colorectal cancer (CRC) is one of the principal causes of cancer‑associated mortality
worldwide. The high incidence of liver metastasis is the leading risk factor of mortality in …

Abstract Background Matrix metalloproteinase-8 (MMP-8) is a protease mainly expressed by
neutrophils that cleaves numerous substrates, including collagens and cytokines. We have …