Ageing is accompanied by decrements in the size and function of skeletal muscle that
compromise independence and quality of life in older adults. Developing therapeutic …

The decline in muscle mass and strength with age is well documented and associated with
weakness, decreased flexibility, vulnerability to diseases and/or injuries, and impaired …

Skeletal muscle contractile function is impaired in menopause and exercise may mitigate
this decline. We used the 4-vinylcyclohexene diepoxide (VCD) model of menopause to …

Age-related alterations of skeletal muscle are numerous and present inconsistently, and the
effect of their interaction on contractile performance can be nonintuitive. Hill-type muscle …

Objective Menopause is associated with impaired skeletal muscle contractile function. The
temporal and mechanistic bases of this dysfunction are unknown. Using a mouse model of …

Purpose It is suggested that the early phase (< 50 ms) of force development during a muscle
contraction is associated with intrinsic contractile properties, while the late phase (> 50 ms) …

Improved Ca2+ sensitivity has been suggested as a mechanism behind enhancements in
muscle mechanical function following eccentric training. However, little is known regarding …

Intense exercise training with insufficient recovery time is associated with reductions in
neuromuscular performance. However, it is unclear how single muscle fibre mechanical …

Aging is associated with impaired strength and power during isometric and shortening
contractions, however, during lengthening (ie, eccentric) contractions, strength is …

Degenerative spinal disorders, including kyphotic deformity, are associated with a range of
degenerative characteristics of the paraspinal musculature. It has therefore been …