Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …

Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …

Cardiovascular diseases (CVDs) are the leading global cause of mortality and disability,
tending to happen in younger individuals in developed countries. Despite improvements in …

The falsification of data related to c-kit+ cardiac progenitor cells (CPCs) by a Harvard
laboratory has been a veritable tragedy. Does this fraud mean that CPCs are not beneficial …

This review article discusses the special role that melatonin, a molecule with chronobiotic/
cytoprotective properties, may have in prevention and treatment of the metabolic syndrome …

Chronic hypobaric hypoxia during fetal and neonatal life induces neonatal pulmonary
hypertension. Hypoxia and oxidative stress are driving this condition, which implies an …

A circadian disruption, manifested by disturbed sleep and low-grade inflammation, is
commonly seen in noncommunicable diseases (NCDs). Cardiovascular, respiratory and …

Melatonin, an emphatic endogenous molecule exerts protective effects either via activation
of G-protein coupled receptors (Melatonin receptors, MTR 1–3), tumor necrosis factor …

Signal transducer and activator of transcription 3 (STAT3), an important transcription factor
and signaling molecule, play an important role in cardiac disease and protection. As a …

Cardiotoxicity is one of the primary limitations in the clinical use of the anticancer drug
doxorubicin (DOX). However, the role of microRNAs (miRNAs) in DOX-induced …