Lysyl oxidase family enzymes and their role in tumor progression

T Liburkin-Dan, S Toledano, G Neufeld - International journal of molecular …, 2022 - mdpi.com
The five genes of the lysyl oxidase family encode enzymes that covalently cross-link
components of the extracellular matrix, such as various types of collagen and elastin, and …

TIMP-3 as a therapeutic target for cancer

CW Su, CW Lin, WE Yang… - Therapeutic advances in …, 2019 - journals.sagepub.com
Tissue inhibitor of metalloproteinase-3 (TIMP-3), a secreted glycoprotein, plays an important
role in carcinogenesis. It can bind to many proteinases to suppress their activity and thus …

Flavonoids as regulators of TIMPs expression in cancer: Consequences, opportunities, and challenges

L Cayetano-Salazar, DA Nava-Tapia… - Life Sciences, 2022 - Elsevier
Cancer is one of the leading causes of death in patients worldwide, where invasion and
metastasis are directly responsible for this statement. Although cancer therapy has …

Cervical cancer stem cells and other leading factors associated with cervical cancer development

G Mendoza-Almanza, E Ortiz-Sanchez… - Oncology …, 2019 - spandidos-publications.com
Cervical cancer (CC) is one of the leading causes of cancer-associated mortalities in women
from developing countries. Similar to other types of cancer, CC is considered to be a …

Changes in the extracellular matrix in endometrial and cervical cancer: a systematic review

T Padežnik, A Oleksy, A Cokan, I Takač… - International Journal of …, 2023 - mdpi.com
Endometrial and cervical cancers are the two most common gynaecological malignancies
and among the leading causes of death worldwide. The extracellular matrix (ECM) is an …

Targeting cervical cancer stem cells by phytochemicals

T Tripathi, J Yadav, D Janjua… - Current Medicinal …, 2024 - benthamdirect.com
Cervical cancer (CaCx) poses a significant global health challenge, ranking as the fourth
most common cancer among women worldwide. Despite the emergence of advanced …

[HTML][HTML] Unveiling diagnostic and therapeutic strategies for cervical cancer: biomarker discovery through proteomics approaches and exploring the role of cervical …

A Jafari, M Farahani, M Abdollahpour-Alitappeh… - Frontiers in …, 2024 - frontiersin.org
Cervical cancer (CC) is a major global health problem and leading cause of cancer deaths
among women worldwide. Early detection through screening programs has reduced …

Identification of New Key genes and their association with breast Cancer occurrence and poor survival using in Silico and in Vitro methods

R Ali, A Sultan, R Ishrat, S Haque, NJ Khan, MA Prieto - Biomedicines, 2023 - mdpi.com
Breast cancer is one of the most prevalent types of cancer diagnosed globally and continues
to have a significant impact on the global number of cancer deaths. Despite all efforts of …

The repertoire of tissue inhibitors of metalloproteases: evolution, regulation of extracellular matrix proteolysis, engineering and therapeutic challenges

S Costa, MA Ragusa, G Lo Buglio, SD Scilabra… - Life, 2022 - mdpi.com
Tissue inhibitors of metalloproteases (TIMPs) belong to a fascinating protein family
expressed in all Metazoa. They act as regulators of the turnover of the extracellular matrix …

Cervical cancer stem‐like cells: systematic review and identification of reference genes for gene expression

RP de Campos, IC Schultz… - Cell Biology …, 2018 - Wiley Online Library
Cervical cancer is the fourth most common cancer affecting women worldwide. Among many
factors, the presence of cancer stem cells, a subpopulation of cells inside the tumor, has …