Assessment of hypolipidemic and anti‐inflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in triton …

E Palabıyık, AN Sulumer, H Uguz, B Avcı… - Journal of Molecular …, 2023 - Wiley Online Library
Atherosclerosis and cognitive impairment are both influenced by hyperlipidemia. Due to
their high margin of safety and low cost, natural chemicals have recently attracted particular …

Food-derived peptides as novel therapeutic strategies for NLRP3 inflammasome-related diseases: a systematic review

Z Zhang, Y Zhang, M Zhang, C Yu, P Yang… - Critical Reviews in …, 2023 - Taylor & Francis
Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3), a member of the
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …

Gossypin: a flavonoid with diverse pharmacological effects

B Song, X Shen, C Tong, S Zhang… - Chemical Biology & …, 2023 - Wiley Online Library
Gossypin is a flavonoid compound prepared from chinese medicine Hibiscus, which not only
has significant pharmacological activities in antioxidant, anti‐inflammatory, neuroprotective …

Exosomes derived from ADSCs attenuate sepsis-induced lung injury by delivery of circ-fryl and regulation of the miR-490-3p/SIRT3 pathway

W Shen, X Zhao, S Li - Inflammation, 2022 - Springer
Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar
epithelium cells (AECs). Previous investigations illustrate that exosomes secreted from …

Mitochondrial Coenzyme Q Protects Sepsis‐Induced Acute Lung Injury by Activating PI3K/Akt/GSK‐3β/mTOR Pathway in Rats

R Li, T Ren, J Zeng - BioMed research international, 2019 - Wiley Online Library
The aim of our study was to assess the effects of mitochondrial coenzyme Q (MitoQ) on
sepsis‐induced acute lung injury (ALI) and investigate its possible mechanisms. The cecal …

In vivo and in vitro cardioprotective effect of gossypin against isoproterenol-induced myocardial infarction injury

I Cinar, M Yayla, T Tavaci, E Toktay, RA Ugan… - Cardiovascular …, 2022 - Springer
The aim of the study was to examine the protective effects and possible mechanism of
gossypin against isoproterenol (ISO)-mediated myocardial damage in vivo and H9c2 cell …

Pyrroloquinoline quinone (PQQ) alleviated sepsis-induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression

Y Wu, M Zhao, Z Lin - Bioengineered, 2021 - Taylor & Francis
ABSTRACT PQQ has anti-inflammatory and anti-oxidant effects. PQQ can relieve high
glucose-induced renal cell damage by suppressing Keap1 expression. Keap1 can interact …

Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats

M Savran, R Aslankoç, O Ozmen, Y Erzurumlu… - Cytokine, 2020 - Elsevier
Sepsis, systemic hyper-inflammatory immune response, causes the increase of morbidity
and mortality rates due to multi-organ diseases such as neurotoxicity. Lipopolysaccharide …

[HTML][HTML] Acacia nilotica stem bark extract ameliorates obesity, hyperlipidemia, and insulin resistance in a rat model of high fat diet-induced obesity

SS Khalaf, OA Shalaby, AR Hassan… - Journal of traditional and …, 2023 - Elsevier
Background and aim Acacia nilotica (A. nilotica) is an imperative plant with many medicinal
uses. The current study aimed to investigate the protective effects of the stem bark of A …

Suppression of NOD-like receptor protein 3 inflammasome activation and macrophage M1 polarization by hederagenin contributes to attenuation of sepsis-induced …

L Wang, M Zhao - Bioengineered, 2022 - Taylor & Francis
Acute lung injury (ALI) is a major leading cause of death in sepsis patients. Hederagenin
(HG), derived from Hedera helix Linné, has anti-inflammatory effects, while its role in sepsis …