Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are members of a tumor
family consistently associated with chromosomal translocation and functional fusion of the …

Ewing sarcoma is a primary bone tumor initiated by EWSR1–ETS gene fusions. To identify
secondary genetic lesions that contribute to tumor progression, we performed whole …

The Ewing sarcoma family of tumors (EFT) is a group of highly malignant small round blue
cell tumors occurring in children and young adults. We report here the largest genomic …

The identification of subtype-specific translocations has revolutionized the diagnostics of
sarcoma and has provided new insight into oncogenesis. We used RNA-seq to investigate …

This review summarizes reports of recurrent DNA sequence copy number amplifications in
human neoplasms detected by comparative genomic hybridization. Some of the …

The advent of dose intensified interval compressed therapy has improved event-free survival
for patients with localized Ewing sarcoma (EwS) to 78% at 5 years. However, nearly a …

The identification of the non-random chromosome rearrangements between the EWS gene
on chromosome 22q12 and members of the ETS gene family in Ewing's sarcoma, peripheral …

Tumor development is a complex process resulting from interplay between mutations in
oncogenes and tumor suppressors, host susceptibility factors, and cellular context. Great …

Hepatocellular carcinoma (HCC) is a common and highly malignant tumor that is prevalent
in Southeast Asia. Although the etiological factors associated are now well recognized, the …