Accelerating the design of nucleic acid amplification methods remains a critical challenge in
the development of molecular tools to identify biomarkers to diagnose both infectious and …

Background In the process of retrotransposition LINEs use their own machinery for copying
and inserting themselves into new genomic locations, while SINEs are parasitic and require …

The thermal stabilities of DNA duplexes analogous to the let-7 microRNA: lin-41 mRNA
complex from Caenorhabditis elegans have been measured by free solution capillary …

Diagnostic tests have the power to detect disease and determine treatments. Recent
diagnostic innovations have focused on technological advancements to decrease …

Multitasking is the pivotal feature in next-generation chemo-or bioanalyses. However,
simultaneous analyses rarely exceed over three different tasks, which is ascribed to the …

Diagnostic tests can detect diseases, monitor responses, and inform treatments. They are
vital to the effective management of disease. There have been significant advances in the …

Internal loops within structured nucleic acids disrupt local base stacking and destabilize
neighboring helical domains; however, these structural motifs also expand the …

In this fundamental research, we found that homo-oligo based dsDNA holds potential
electrochemical characteristics in comparison to hetero-oligo based dsDNA which can be …

This thesis details the implementation of various fluorescence techniques in combination
with an anti-Brownian electrokinetic (ABEL) trap to examine the conformations and …

Les récentes découvertes de l'implication des acides nucléiques dans un large éventail de
processus biologiques ont révélé l'importance de pouvoir les détecter et les localiser …