Exosome‐encapsulated microRNAs as circulating biomarkers for breast cancer

DP Joyce, MJ Kerin, RM Dwyer - International journal of cancer, 2016 - Wiley Online Library
Breast cancer is a highly prevalent disease, accounting for 29% of invasive cancers in
women. Survival from this disease depends on the stage at diagnosis, with patients who are …

A perspective on extracellular vesicles proteomics

L Rosa-Fernandes, VB Rocha, VC Carregari… - Frontiers in …, 2017 - frontiersin.org
Increasing attention has been given to secreted extracellular vesicles (EVs) in the past
decades, especially in the portrayal of their molecular cargo and role as messengers in both …

Characterisation of extracellular vesicle-subsets derived from brain endothelial cells and analysis of their protein cargo modulation after TNF exposure

V Dozio, JC Sanchez - Journal of extracellular vesicles, 2017 - Taylor & Francis
Little is known about the composition and functional differences between extracellular
vesicle (EV) subsets, such as microvesicles (MVs) and exosomes (EXOs), nor to what extent …

Next-Cell Hypothesis: Mechanism of Obesity-Associated Carcinogenesis

AB Engin, A Engin - Obesity and Lipotoxicity, 2024 - Springer
Higher body fat content is related to a higher risk of mortality, and obesity-related cancer
represents approximately 40% of all cancer patients diagnosed each year. Furthermore …

Dark-side of exosomes

A Engin - Protein Kinase-mediated Decisions Between Life and …, 2021 - Springer
Exosomes are nanoscale extracellular vesicles that can transport cargos of proteins, lipids,
DNA, various RNA species and microRNAs (miRNAs). Exosomes can enter cells and deliver …

A facile “one-material” strategy for tandem enrichment of small extracellular vesicles phosphoproteome

F Jiao, F Gao, Y Liu, Z Fan, X Xiang, C Xia, Y Lv, Y Xie… - Talanta, 2021 - Elsevier
Small extracellular vesicles (SEVs), are cell-derived, membrane-enclosed nanometer-sized
vesicles that play vital roles in many biological processes. Recent years, more and more …

Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport

J Zhang, JK Karimy, E Delpire… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: The mammalian SPS1-related proline/alanine-rich serine-threonine kinase
SPAK (STK39) modulates ion transport across and between epithelial cells in response to …

Role of Cl–HCO3 exchanger AE3 in intracellular pH homeostasis in cultured murine hippocampal neurons, and in crosstalk to adjacent astrocytes

AI Salameh, CA Hübner, WF Boron - The Journal of Physiology, 2017 - Wiley Online Library
Key points A polymorphism of human AE3 is associated with idiopathic generalized
epilepsy. Knockout of AE3 in mice lowers the threshold for triggering epileptic seizures. The …

[图书][B] Function of Surface-Associated Protein and DNA on Extracellular Vesicles

G Shelke - 2018 - gupea.ub.gu.se
Extracellular vesicles (EVs), including exosomes, are nano-sized, lipid bilayer enclosed
vesicles that are released into the extracellular environment from by almost all cells. EVs …

[HTML][HTML] The mysterious role of the neuronal anion exchanger‐3

E Delpire - The Journal of Physiology, 2017 - ncbi.nlm.nih.gov
Neurons and astrocytes continuously consume ATP to maintain the composition of their
intracellular milieu and to a lesser degree, their extracellular environment. This includes the …