Rat studies suggest that artemisinin‐induced decreases in reticulocyte count are a marker
for embryotoxicity (in one study, r= 0.82; p< 0.05). In clinical studies, therapeutic doses of …

The comparative effect of Chloroquine and Artesunate; two drugs commonly used in the
prophylaxis and chemotherapy of malaria on the haematology and serum biochemistry of …

The fact that mitochondria still have metabolic activity and can live for a week with
appropriate nutrients after isolated from the rat liver provides us a useful means to …

The recent resurgence of interest in the study of mitochondria has been fuelled in large part
by the recognition that genetic and/or metabolic alterations in this organelle are causative or …

In this study, the metabolic thermogenic curves of mitochondria isolated from rat liver tissue
were drawn, and the effects of artesunate on metabolic activity of mitochondria were studied …

The challenges of free radicals and tumour promoting agents are on the increase and this
informed investigation of the antioxidant property and anticancer potential of Vernonia …

This study investigated the effect of coartemether on antioxidant and hepatotoxic biomarkers
in Plasmodium berghei infected mice. Erythrocyte, hepatic and renal superoxide dismutase …

Malaria is a common disease of humans caused by different species of plasmodium.
Artemisinin derivatives li e artemether and coartem are being used to treat malaria. The …

Objective: This study investigated the effects of oral co-administered ascorbic acid (AA) and
dihydroartemisinin (DHA) on some hepatotoxic biomarkers and parasitaemia counts in …

It has been demonstrated that artesunate causes hepatoxicity by inducing opening of the
mitochondrial permeability transition (MPT) pore; a condition that is exacerbated by ferrous …