[HTML][HTML] Tarnished gold—the “standard” urine culture: reassessing the characteristics of a criterion standard for detecting urinary microbes
L Brubaker, TC Chai, H Horsley, R Khasriya… - Frontiers in …, 2023 - frontiersin.org
Diagnosis and treatment of urinary tract infections (UTIs) remains stagnant. The presumption
that a patient either has a UTI or does not (binary choice) is inappropriately simplistic …
that a patient either has a UTI or does not (binary choice) is inappropriately simplistic …
Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double …
F Wagenlehner, CR Perry, TM Hooton… - The Lancet, 2024 - thelancet.com
Background Gepotidacin is a novel, bactericidal, first-in-class triazaacenaphthylene
antibiotic that inhibits bacterial DNA replication by a distinct mechanism of action and a …
antibiotic that inhibits bacterial DNA replication by a distinct mechanism of action and a …
[HTML][HTML] Elevated UTI biomarkers in symptomatic patients with urine microbial densities of 10,000 CFU/ml indicate a lower threshold for diagnosing UTIs
The literature lacks consensus on the minimum microbial density required for diagnosing
urinary tract infections (UTIs). This study categorized the microbial densities of urine …
urinary tract infections (UTIs). This study categorized the microbial densities of urine …
Current and emerging strategies to curb antibiotic-resistant urinary tract infections
A Simoni, L Schwartz, GY Junquera, CB Ching… - Nature Reviews …, 2024 - nature.com
Rising rates of antibiotic resistance in uropathogenic bacteria compromise patient outcomes
and prolong hospital stays. Consequently, new strategies are needed to prevent and control …
and prolong hospital stays. Consequently, new strategies are needed to prevent and control …
[HTML][HTML] The Essential Role of PCR and PCR Panel Size in Comparison with Urine Culture in Identification of Polymicrobial and Fastidious Organisms in Patients with …
X Hao, M Cognetti, C Patel, N Jean-Charles… - International Journal of …, 2023 - mdpi.com
Complicated urinary tract infections (cUTIs) are difficult to treat, consume substantial
resources, and cause increased patient morbidity. Data suggest that cUTI may be caused by …
resources, and cause increased patient morbidity. Data suggest that cUTI may be caused by …
Under the Hood: The Scientific Leadership, Clinical Operations, Statistical and Data Management, and Laboratory Centers of the Antibacterial Resistance Leadership …
HR Cross, KE Greenwood-Quaintance… - Clinical Infectious …, 2023 - academic.oup.com
Developing and implementing the scientific agenda of the Antibacterial Resistance
Leadership Group (ARLG) by soliciting input and proposals, transforming concepts into …
Leadership Group (ARLG) by soliciting input and proposals, transforming concepts into …
[HTML][HTML] Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia …
R Yao, X Mao, Y Xu, X Qiu, L Zhou, Y Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
The seeds of Vaccaria segetalis (Neck.) are from a traditional medicinal plant Garcke, also
called Wang-Bu-Liu-Xing in China. According to the Chinese Pharmacopoeia, the seeds of …
called Wang-Bu-Liu-Xing in China. According to the Chinese Pharmacopoeia, the seeds of …
[HTML][HTML] Rapid pathogen identification and phenotypic antimicrobial susceptibility directly from urine specimens
L Burg, G Crewe, J DiMeo, X Guo, CG Li, M Mayol… - Scientific Reports, 2022 - nature.com
Implementing effective antimicrobial therapy close to the onset of infection lowers morbidity
and mortality and attenuates the spread of antimicrobial resistance. Current antimicrobial …
and mortality and attenuates the spread of antimicrobial resistance. Current antimicrobial …
Proposing the “Continuum of UTI” for a Nuanced Approach to Diagnosis and Management of Urinary Tract Infections
Purpose: Patients with suspected UTIs are categorized into 3 clinical phenotypes based on
current guidelines: no UTI, asymptomatic bacteriuria (ASB), or UTI. However, all patients …
current guidelines: no UTI, asymptomatic bacteriuria (ASB), or UTI. However, all patients …
[PDF][PDF] Proposing the “Continuum of Urinary Tract Infection (UTI)” for a Nuanced Approach to Diagnosis and Management of UTIs
Purpose: Patients with suspected urinary tract infections (UTIs) are categorized into three
clinical phenotypes based on current guidelines: no UTI, asymptomatic bacteriuria (ASB), or …
clinical phenotypes based on current guidelines: no UTI, asymptomatic bacteriuria (ASB), or …