Consistency-based thresholding of the human connectome
Densely seeded probabilistic tractography yields weighted networks that are nearly fully
connected, hence containing many spurious fibers. It is thus necessary to prune spurious …
connected, hence containing many spurious fibers. It is thus necessary to prune spurious …
Effects of statins on memory, cognition, and brain volume in the elderly
K Samaras, SR Makkar, JD Crawford… - Journal of the American …, 2019 - jacc.org
Background: There is widespread consumer concern that statin use may be associated with
impaired memory and cognitive decline. Objectives: This study sought to examine the …
impaired memory and cognitive decline. Objectives: This study sought to examine the …
Comparison of single phase and biphasic extraction protocols for lipidomic studies using human plasma
Lipidomic profiling of plasma is an emerging field, given the importance of lipids in major
cellular pathways, and is dependent on efficient lipid extraction protocols. Recent attention …
cellular pathways, and is dependent on efficient lipid extraction protocols. Recent attention …
[HTML][HTML] Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models
Alzheimer's disease (AD) is marked by cognitive dysfunction emerging from
neuropathological processes impacting brain function. AD affects brain dynamics at the local …
neuropathological processes impacting brain function. AD affects brain dynamics at the local …
[HTML][HTML] Risk factors for falls in community-dwelling older people with mild cognitive impairment: a prospective one-year study
Objective Mild cognitive impairment (MCI) is considered an intermediate stage between
normal cognitive function and dementia. Fall risk is increased in this group, but there is …
normal cognitive function and dementia. Fall risk is increased in this group, but there is …
The independent influences of age and education on functional brain networks and cognition in healthy older adults
Healthy aging is accompanied by a constellation of changes in cognitive processes and
alterations in functional brain networks. The relationships between brain networks and …
alterations in functional brain networks. The relationships between brain networks and …
Latent classes of neuropsychiatric symptoms in NACC controls and conversion to mild cognitive impairment or dementia
JMS Leoutsakos, SN Forrester… - Journal of …, 2015 - journals.sagepub.com
Background: A number of studies have linked neuropsychiatric symptoms to increase risk of
dementia. Objective: To determine if risk of conversion to mild cognitive impairment or …
dementia. Objective: To determine if risk of conversion to mild cognitive impairment or …
The organisation of the elderly connectome
Investigations of the human connectome have elucidated core features of adult structural
networks, particularly the crucial role of hub-regions. However, little is known regarding …
networks, particularly the crucial role of hub-regions. However, little is known regarding …
State-switching and high-order spatiotemporal organization of dynamic functional connectivity are disrupted by Alzheimer's disease
Spontaneous activity during the resting state, tracked by BOLD fMRI imaging, or shortly
rsfMRI, gives rise to brain-wide dynamic patterns of interregional correlations, whose …
rsfMRI, gives rise to brain-wide dynamic patterns of interregional correlations, whose …
Imaging and neuropsychological correlates of white matter lesions in different subtypes of mild cognitive impairment: a systematic review
CLM Lam, J Yiend, TMC Lee - NeuroRehabilitation, 2017 - journals.sagepub.com
BACKGROUND: White matter lesions (WML) are prevalent in older adults. The association
between WML and cognition in different subtypes of Mild Cognitive Impairment (MCI) is …
between WML and cognition in different subtypes of Mild Cognitive Impairment (MCI) is …