Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment.
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …

During tumor development, invasion and metastasis, the intimate interaction between tumor
and stroma shapes the tumor microenvironment and dictates the fate of tumor cells. Stromal …

Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive and
lethal malignancies worldwide with an urgent need for new diagnostic and therapeutic …

Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis
and limited treatment options. Serine hydrolases are known to mediate cancer progression …

Pancreatic cancer is a devastating malignancy with minimal treatment options. Standard‐of‐
care therapy, including surgery and chemotherapy, is unsatisfactory, and therapies …

Kallikrein-related peptidases (KLKs) are implicated in many cancer-related processes.
KLK6, one of the 15 KLK family members, is a promising biomarker for diagnosis of many …

Introduction Human kallikrein-related peptidases (KLKs) represent a subgroup of 15 serine
endopeptidases involved in various physiological processes and pathologies, including …

Targeted therapies for prostate, breast, and ovarian cancers are based on their activity
against primary tumors rather than their anti‐metastatic activity. Consequently, there is an …

Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …